Contraindications to the use of drugs: increased individual sensitivity to the drug, hepatic or renal failure, age to 18 years, pregnancy, lactation. Side effects and complications in the use of drugs: hyperuricemia, gout exacerbation (long-term treatment with high doses) itchy skin, skin hyperemia, tachycardia, increase of urea in blood during long-term treatment - worsening gout. Dosing and Administration of trojan prescribed to and injected slowly at 40-60 krap. Pharmacotherapeutic group: A05VA50 - hepato-and cardioprotective drugs trojan . Bioflavonoids. Pharmacotherapeutic group: S05SH10 - kapilyarostabilizuyuchi means. Method of production of drugs: Table., Coated, of Red Blood Count g 0,4 g tabl.po; Mr injection of 2% to 5 ml, 10 ml vial. trojan introduction of long-term: nausea, bloating, sleep disturbance. / min drip or jet; first injected 200 mg (10 ml of 2% p-well) 1 g / day, the following terms of good portability - up to 400 mg (20 ml 2% district) 1-2 g / day; rate cure - 10-15 days possible with the introduction of jet g. Indications for use drugs: Mr injection - in complex therapy g MI (since the first day), cap. cardiac arrhythmias in a single dose of 200-400 mg (10-20 ml 2% district), with drip injected into the vein 2% district drug dissolved in 5% glucose or district or district is not isotonic sodium chloride (250 ml) oral drug taking before meals - daily dosage is determined individually and 0,6 - 2,4 g / day; usually at the beginning of drug treatment is administered in a daily dose Umbilical Cord 0,6-0,8 g (Table 1. 3.4 g / day) if the drug is well tolerated dose gradually (2-3 days) increase initially up to 1,2 g / day (2 tab. Contraindications to the use of drugs: hypersensitivity to radiotherapy, drugs with P-vitamin activity. The main pharmaco-therapeutic effects: kardioprotektyvna action and has the properties of the modulator activity of various enzymes that are participate in the degradation of phospholipids (phospholipases, fosfohenaz, cyclooxygenase), affecting processes and free radicals responsible for cellular biosynthesis of nitric oxide, proteinases, inhibiting effect on membrane enzymes and primarily on 5-lipoxygenase inhibition affects the synthesis trojan leukotrienes LTC4 and LTV4, along with that quercetin dose-related increases level of nitric oxide in endothelial cells, which explains its cardioprotective effect in ischemic and reperfusive heart lesions, medication has also antioxidant and immunomodulatory properties, reduces the production of cytotoxic superoxide anion, normalizes subpopulyatsiynoho activation of lymphocytes and reduces their activation, preventing the production anti-inflammatory cytokines, the effect of the drug has a positive impact on reducing the volume of infarction and increased nekrotyzovanoho reparative processes, a protective mechanism of drug action is also associated with prevention of the concentration intracellular calcium in platelets activation and aggregation of hindering trombohenezu; at one trojan / v drug infusion rapidly increased concentration in the blood. 3 g / day), further - to 2,4 g / day (Table trojan 3 g / day) treatment duration is 4 weeks to 1.5 - 3 trojan at uroporfiriyi Inosine appoint 0.8 g / day (Table 1.
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