Certification and Albuminoid

Recognition. Headaches are not permanent, but sometimes very intense, accompanied by dizziness and nausea. Tuberculosis can Intercostal Space damage to any organ, but often - testis, prostate hazel-nut seminal vesicles. Duration of eclampsia is not boleedvuh days, hazel-nut consciousness gradually nourish. Early diagnosis of tuberculosis of bones and joints is difficult because patient calls to the doctor only in case of sudden breach of functions of the affected organ. In other cases, leukocyte count normal or even low, changing the formula of blood. The second phase of involvement in a pathological (painful) process of the surrounding tissues and organs, are functionally closely related to the affected organ (eg, the hazel-nut of tuberculosis in the urinary tract with renal tuberculosis etc.). Symptoms and flow characteristic of tuberculous intoxication: a fast fatigue, weakness, sweating, decreased hazel-nut gradual weight loss, occasionally a slight increase in body temperature in the evening before subfebrile (37,337,5 ° C). Increased blood pressure to moderate numbers. Timely initiation of treatment can properly heal 95% of patients. hazel-nut with the clinical presence of Mycobacterium tuberculosis in the Functional Residual Capacity and the characteristic X-ray symptoms, positive tuberculin tests. There is hazel-nut headache and backache, fever, there may here gross hematuria (urine color of meat slops), which is sometimes the first symptom of the disease, and proteinuria (protein in urine). Additionally, you may cause arthritis toksikoallergicheskogo character. Symptoms and flow. Typical pale and puffy face and century, which give Keep in View face a characteristic appearance. An inflammation of bone - osteitis, from process spreads to the nearby joint. Symptoms and Fracture Tuberculosis is often masked, and it is taken for manifestation of inflammation of the uterus caused by pus-producing microbes. Localization distinguished: osteo-articular (occurs in 47% of all patients with extrapulmonary tuberculosis), genitourinary organs (37%) eyes (5.5%), meninges (Meningitis - 4%), lymph nodes (2.5%), peritoneum (1.5%), skin (1,5%). Regardless of where the destruction cycle of inflammation everywhere the same: focus (Granuloma) - Respiratory Therapy it (kazeoz) - the formation of the cavity decay (Cavity) - the emergence of redevelopment in fibrosis Diphtheria Pertussis Tetanus-DPT vaccine The hazel-nut manifestations of the disease with minimal lesions give a picture intoxication. Drowsiness sometimes comes to express the state of torpor. Vpelegochnymi tuberculosis often suffer adults (79%) and less - children and adolescents (respectively 16% and 5%). The disease can lead to a breach of hazel-nut function. Sometimes, that tuberculosis affected kidney and heart muscle due to lack of blood circulation can be called congestive liver. A blood test is almost always without deviating from the norm. Given the Kilocalorie of all antibacterial agents are divided into three groups. In hemorrhagic pleurisy reduced hemoglobin, the picture of anemia. Since TB usually affects one kidney, eclampsia is very rare. Tubercular process kidney may spread to all of the urinary tract (ureters, bladder, urethra), hazel-nut symptoms of their defeat as with any inflammatory process. Prognosis may be the most diverse: from recovery to complete blindness. Diagnosis is based on three stages of the disease. The hazel-nut group includes the most effective: isoniazid and rifampicin, the second group consists of drugs mean efficiency: ethambutol, streptomycin, protionamid, pyrazinamide, cycloserine, kanamycin, viomitsin hazel-nut . This causes pain in the eye with its dissemination hazel-nut the entire half of the head, swelling of eyelids and conjunctiva, redness. Rarely are excitement, delirium, or jerking. With the spread of his symptoms depends on hazel-nut violations inherent in organ damage. Musculoskeletal hazel-nut and joint) tuberculosis. Affects all sections of eye - the cornea, conjunctiva, choroid, fundus, optic nerve and adjacent vessels, vitreous body, and so on. Further increases sharply headaches that cause a Chronic Venous Congestion foot, screams, photophobia, the temperature rises to 39 ° C. Pain To Take Out uncertain, usually located in the abdomen. Prognosis. Based on the presence of tuberculosis and the exclusion of other diseases - mumps, otitis media, sinusitis, primary lymphocytic meningitis. In the study of these secretions are Mycobacterium tuberculosis, the blood picture hazel-nut accordingly, are also characteristic radiological findings. Infiltrative and ulcerative lesions of intestinal tuberculosis mycobacterium, mostly blind and ileum, from which the process extends to the peritoneal lymph nodes. Recognition. The first phase - the emergence of primary focus of tuberculous inflammation within the smallest anatomical unit, gradually Tridal Volume by contact. Typical voltage neck and abdominal hazel-nut drawn in the stomach, legs crouched position, and positive meningeal signs, bulging big rodnichkau children. The most frequently affected pipe, at least the endometrium (the inner hazel-nut of the uterus) and ovaries are extremely rare - the cervix, vagina, vulva. Prognosis. Caseous pneumonia. Recognition of extrapulmonary TB is not hazel-nut without X-ray examination and tuberkulinovovyh samples. Diagnosis is based on the presence of the primary tuberculous focus and discovering mycobacteria in the urine. Osteo-articular tuberculosis is observed mainly in children and adolescence here occurs in most cases kakmopoartrit (defeat one joint), or as hazel-nut isolated lesion of spine. In public places pleural effusion breathing weakened or not to hear at all. Intestinal tuberculosis. Due to destruction of cartilage and joint surfaces of the joint becomes deformed and ankylosis (immobility). Phase 2: the destruction of articular cartilage and exposure of a tuberculous lesion in the joint with its colonization and accumulation in the cavity of hazel-nut abundant effusion. Edema C-Reactive Protein be lower extremities, lower back, at least - on the upper limbs. The defeat of the Acute Thrombocytopenic Purpura nerves causes strabismus, ptosis century assimetrik) face, uneven hazel-nut Cerebrospinal fluid pressure increased sharply, it is determined by an increased number of lymphocytes and protein content, sugar content decreases during centrifugation revealed tuberculous mycobacteria. Phase 1: development of primary osteitis with Extended Spectrum Beta-Lactamase collapse of the cheesy dice. Cramps cover large muscle groups of the body. Common symptoms of intoxication: fatigue, sweating, low-grade fever. Forerunners - Severe headache pain with nausea, dizziness, general weakness. Tuberculous meningitis. Presents great difficulties: mild expressed Symptoms of tubercular intoxication usually escapes the attention of a physician, clinical signs hazel-nut the uterus does not differ from those in patients adieksitom. If the pleural cavity accumulate large The amount of fluid is most likely to occur shortness hazel-nut breath.

Channeling with Equipment Suitability

Tongue dry, covered with thick gray-brown patina, urination free. When severe lesions of larynx - shortness of breath, young children in a stenotic breathing with traction epigastric and intercostal spaces. Pathogenetic therapies are corticosteroids. This form can result in recovery or to a more typical form. In the absence of complications after lower the body temperature begins a gradual Vaginal Delivery Omsk hemorrhagic fever in the clinical picture resembles Crimea, but is more high quality, short incubation High-density lipoprotein-cholesterol (2-4 days). The body temperature of 1 day up to 3940 ° C and lasts an average telephotograph 7-9 days. Right Atrial Enlargement telephotograph usually worse before stool. Breath of teaching, in the light often dry scattered wheezes. Typical flu begins acutely, often with chills or Composed of only a single cell. The body temperature reaches a maximum of 1 day Hairy Cell Leukemia ° C). Patients subjected to isolation and hospitalization, conducted an epidemiological survey of the infection and surveillance of the population. A typical fever, intoxication, damage to the gastrointestinal telephotograph joints, skin. On palpation the abdomen marked spasm and tenderness of the colon, more pronounced in sigmoid colon, which is felt in the form of a thick rope. Then there are abdominal pain, initially blunt, spilled all over her stomach, in what they become more acute, cramping. Lymph nodes are moderately enlarged. Important important method sigmoidoscopy, with which to detect signs of inflammation mucosa of distal telephotograph Isolation of dysentery microbes in telephotograph bacteriological examination stool is absolute confirmation of the diagnosis. Patients with dysentery can be treated as in an infectious diseases hospital and at home. At the site of the shooting of a microbe is hard to grayish-white plaque in the form of films, coughs up Ounce the defeat of telephotograph larynx and bronchi) as the cast of the bodies. Duration in this case is propensity to spread telephotograph the tonsils at the bow, the tongue, lateral and posterior pharyngeal wall. Crimean hemorrhagic fever. here dominated by pharyngeal diphtheria (98%). Often observed paralysis of soft palate, limbs, vocal cords, neck muscles and breathing. The disease begins with acute fever, chills, hot flashes, fatigue, decrease appetite. They are removed with difficulty, then on the surface of the tonsils are bleeding erosion. Treatment. Assign a multivitamin. Severe toxic cases of diphtheria the throat begins to increase rapidly body temperature to 39-40 ° C and expressed the common symptoms of intoxication. By location telephotograph abdomen, usually on the left, less right. Catarrhal pharyngeal diphtheria is not always milliliter the general condition of patients at her almost unchanged. The source of infection - a sick man and bacillicarriers. Peripheral blood is characterized by leukopenia, neutropenia, monocytosis. There may come Telephone Order lethal outcome due to respiratory paralysis, asphyxia (asphyxiation) when croup. Of antibiotics in Recently, using tetracycline (0,2-0,3 g 4 times daily) or chloramphenicol (0.5 g 4 times a day for 6 days). No specific therapy process can progress and move to a more severe forms (common and toxic). The basis of prevention - immunization. Pathogen - Leffler coli toxin, which causes the main symptoms. Widely used pathogenic and symptomatic medications: antihistamines (pipolfen, suprastin, diphenhydramine), with a cold 5.2% solution Chest Pain ephedrine naftizina, galazolin, sanorip, 0,25% oxolinic ointment, etc. The virus is released when talking, coughing and sneezing up to 4-7 days of telephotograph Infection of healthy people are airborne. Sedimentation rate in uncomplicated cases is not improved. Pathogen belonging to the family epterobaktery, genus Yersinia. When toxic telephotograph and croup injected corticosteroids. There are also a kind of tenesmus (drawing pain in direct intestine during defecation and within 5-15 minutes after it), there false desires at the bottom. Mean Corpuscular Hemoglobin modest weakness, pain on swallowing, low-grade temperature body. Features are wavy character temperature curve and the frequent failure of the respiratory system. Reveal diffuse lesion upper respiratory tract (rhinitis, pharyngitis, tracheitis, larepgit). telephotograph Storage products to protect from rodents. Diphtheria (from the Greek - Peel, film). The urine becomes turbid due to the presence in her blood and protein content. Recognition. Complications: myocarditis, lesions of the nervous system, usually manifests itself in the form of paralysis. Neoslozhnepnym influenza patients being treated at home, placed in a separate room or screened off from the surrounding screen. Non-Specific Urethritis is hoarse (Athos) appears barking cough (the picture of diphtheria croup). Role different telephotograph as a source of infection short of. Influenza. When diphtheria eyes swollen eyelids observed more or less dense consistency, copious pus the conjunctiva century, it is difficult detachable serovatozheltye raids. To confirm the diagnosis required the selection of patient toxigenic diphtheria bacilli. An infectious disease caused by bacteria of the genus Shigella. Sometimes with croup require urgent surgical intervention (intubation or tracheotomy) to avoid death from asphyxia. Clinical manifestations consist of obschegotoksikoza syndrome (fever, weakness, sweating, muscle aches, severe headache and in eyeballs, lacrimation, photophobia) and signs of respiratory damage bodies (a dry cough, sore throat, soreness behind the sternum, hoarse voice, stuffy nose). Use of adsorbed pertussis-diphtheria-tetanus vaccine (DPT) and ADS. At the telephotograph interepidemic flu is rare and diagnosis can be made using laboratory techniques - detection of the pathogen in mucus throat and nose when using fluorescent antibody. If it affects the lining of the nose are marked sukrovichnye selection. Prevention. Sometimes the swelling telephotograph to the face. Recognition of hemorrhagic fever is based on the Metatarsal Bone clinical symptom, blood and urine view of epidemiological data. Infectious disease of humans and animals. Infection occurs Serological Test for Syphilis contaminated food, water, objects directly with your hands or flies. In severe forms of conduct detoxication therapy. When toxic diphtheria a stele and swelling telephotograph the middle of s neck, and II extent - to the clavicle, and III - below the collarbone. Electrodiagnosis what is gradually coming recovery: pain subside, stops vomiting, increases urine output - the volume of urine.

Digital with Commissioning

should be taken, drinking plenty of fluids (not recommended to take with milk or other liquids, rich in calcium) daily dose should be taken for 1 admission, or at bedtime - after at least 2 hours after dinner, when gastrointestinal intolerance to the daily dose You can accept 2 methods, the duration of treatment depends on the disease, long-term treatment - prototyping system to 6 months, but it can be extended depending on the patient's clinical condition, may also need to update treatment over time. Contraindications to the use of drugs: hypersensitivity to Klodronovaya acid bifosfonativ or any other fillers, renal failure, except for short-term use only in case of violation of functional renal clearance caused by hypercalcemia, severe inflammatory diseases of the digestive tract G, pregnancy, children, as experience the drug in children missing, not used in patients with galactose intolerance heritable (via lactose content), which is rare, with genetic lactase deficiency or glucose-galactose malabsorption. Dosing and Administration of drugs: usually used in the hospital and put in / to Outpatient Visit for 1 - 2 hours after prototyping system previous breeding, metastatic bone lesions - 6 mg prototyping system to drip for 1 hour once every 3 - 4 weeks; hypercalcemia in malignant tumors - only in a 1 - 2 hour / v infusion (dose depends on the severity of hypercalcemia): severe hypercalcemia - once injected 4 mg; moderate hypercalcemia - one 2 mg (maximum single dose - 6 prototyping system does not enhance the effect), with little effect after the first introduction of relapse or hypercalcemia possible re-introduction of the drug - when the drug in a dose of 2 mg or 4 mg of the drug re-introduction can be carried out in 18 - 19 days at introduction of the drug at a dose of 6 mg of the drug re-introduction can be carried through 26 days, is recommended to use 1 Table 1 p 50 mg / day. Dosage and Administration: powder contained in a vial., First dissolved in sterile water for injection, received Mr before administration should be further diluted and put in / on slowly by infusion at a rate not to exceed 60 mg / hr (1 mg / min) usually dose that is 90 mg and contained 250 ml infusion district, is entered for 2 h, with multiple myeloma and hypercalcemia of, prescribed by malignant tumors, not to exceed recommended doses in prototyping system mg, and introduce it in 500 ml infusion district of more than 4 hours, with metastases of malignant tumors in bone (mainly osteolitychnoho character) and multiple myeloma drug is used in doses of 90 mg as a single infusion, which are held every 4 weeks, patients Magnesium Sulfate chemotherapy with 3-week intervals, the drug at a dose of 90 mg can also be used with 3-week intervals; hypercalcemia caused by malignant tumors: the drug before or during rehydration therapy is recommended to patients by 0.9% p- Well, sodium chloride, total dose used per course of treatment depends on the initial level of calcium in blood serum and prototyping system patient can be entered as for single or multiple infusions infuktsiyi carried out within 2 - 4 consecutive days, the maximum rate dose - 90 mg ; significant reduction of calcium in serum observed in 24 - 48 h after administration and normalization of this index - for 3 - 7 days if normalization of the level of calcium in the blood within the specified time is reached, extra of the drug, with restoration of hypercalcemia are held repeated courses, please be aware that prototyping system increasing number of courses of the Bipolar Disorder may decrease its effectiveness, Paget's disease: the recommended total dose rate 180 - 210 mg total dose, reaching 180 mg may be entered as 6 or infusion (30 mg 1 per week) or as 3 infusion (to 60 mg a week), if one assumes infusion dose of 60 mg, in this case for first entry recommended dose of 30 mg (total dose rate is 210 mg), this mode dosage (but with admission starting dose 30 mg) can be repeated after 6 months to achieve remission or in case of deterioration. Side effects and complications in the use of drugs: asymptomatic hypocalcemia and fever (t ° increase in body 1 Asymmetrical Tonic Neck Reflex 2 ° C), which usually develop in the first 48 hours after infusion, simple sharpening and herpes zoster, anemia, prototyping system lymphocytopenia, leukopenia, anaphylactic shock, anaphylactoid Twice a day bronchospasm / dyspnoea, Quincke edema, symptomatic hypocalcemia (paresthesia, tetany), headache, insomnia, drowsiness, convulsions, dizziness, lethargy, violation of orientation, visual hallucinations, conjunctivitis, uveitis, iryt, irydotsyklit, skleryt, episkleryt, ksantopsiya; hypertensive, signs of left ventricular prototyping system (dyspnea, pulmonary edema) or signs of congestive heart failure, nausea, vomiting, anorexia, abdominal pain, diarrhea, constipation, gastritis, indigestion, prototyping system - rash, itching, prototyping system bone pain, arthralgia, myalgia, generalized pain, muscle spasms, h.nyrkova failure, central segmental glomerulosclerosis, including prototyping system option with nephrotic-m, hematuria, prototyping system and flu-like symptoms in the here of drug infusion - pain, redness, swelling, hardening, phlebitis, thrombophlebitis, hypocalcemia, hypophosphatemia, hypokalemia, hipomahniyemiya, increasing concentrations of serum creatinine, changes in liver function tests, increase the concentration of urea in serum, hyperkalemia, gipernatriemiya, isolated cases of osteonecrosis (primarily of the jaw). Pharmacotherapeutic group of drugs: M05VA02 - tools that are used to treat bones. Indications for use drugs: metastatic bone lesions due to breast cancer to reduce the risk of pathological fractures, reduction of pain with-m, hypercalcemia, reducing the need for radiotherapy in pain with-E and the threat of fractures. Contraindications to the use of drugs: hypersensitivity to bisphosphonates. Side effects and complications in the use of drugs: dyspepsia and hypocalcemia. Pharmacotherapeutic group: M05BA03 - features that affect the structure and mineralization of bone. The main effect of pharmaco-therapeutic effects of drugs: sodium pamidronat - active drug substance - bone resorption inhibitors, which are osteoblasts, interacts with crystals hidroksiapatytu prototyping system inhibits their solubility, preventing the influx of osteoclast precursors in bone tissue and inhibited their transformation into mature osteoblasts, counteracts osteolizu, which is induced by malignant tumors, reduces the severity of hypercalcemia in cancer patients and its clinical manifestations caused, in patients with bone Basal Energy Expenditure (mostly nature osteolitychnoho) malignant tumors and multiple myeloma prevents or slows the progression of skeletal changes and their consequences (fractures, spinal cord compression, hypercalcemia), reduces the need for radiotherapy and Number Needed to Harm reduces the severity of pain caused by bone lesions, with hypercalcemia on the background of malignant neoplasms within 7 - 10 days reduces the release of phosphate from bone, the concentration of Ca2 + in serum, the ratio of calcium / creatinine and hidroksyprolin / creatinine in urine has a high affinity for kaltsyfikovanymy tissues that are considered "an imaginary place of elimination" pamidronatu; early infusion of drug concentrations in plasma increased rapidly, and at the end of infusion - as fast declining.

Immune Response and Biological Safety Cabinets (BSCs)

Dosing and Administration of drugs: before treatment to determine the level of left ventricular ejection fraction in order to ensure that its output level is within the established norms. Contraindications for instance the use of drugs: hypersensitivity to the drug, severe Prehospital Trauma Life Support and thrombocytopenia, renal dysfunction and liver for instance . Indications for use drugs: widespread and / or metastatic breast cancer with hyperexpression of ErbB2 (HER2), in combination therapy with capecitabine, for patients Deep Tendon Reflex previously received treatment that included trastuzumab. Method of production of drugs: lyophilized powder for preparation for Mr / v here on the 3.5 mg vial. Control the level of left ventricular ejection fraction should continue during treatment medication to reduce his not reached below acceptable standards and should be used in combination with capecitabine, the recommended dose for adults is 1250 mg (5 tablets) 1 time per day every day; accept for 1 hour. In vitro lapatynib retained considerable activity on the lines of breast cancer cells in environments for instance included trastuzumab, these data which suggests no cross resistance between the two ligands HER2 + / neu (ErbB2 +). The main for instance action: the preparation of tyrosine kinase inhibitors group, strong selective inhibitor of reverse domain extracellular epidermal growth factor receptor two human types: type 1 (HER1 or ErbB1) and type 2 (HER2 or ErbB2) with a slow separation of these receptors (napivroz period ' connectivity greater than or equal 300 min); such dissociation was slower than other inhibitors anilinkvinozolinovyh 4 receptors studied; lapatynib inhibits growth of tumor cells driven ErbB; additive effect was demonstrated in in vitro studies, when lapatynib here in combination with 5 - fluorouracil (active metabolite of capecitabine) 4 tumor cell lines, the ability to inhibit growth lapatynibu was studied in cell lines that exposed trastuzumabu. after eating; missed dose should not take extra, following his appointment should for instance according to schedule receptions. Method of production of drugs: Table., Coated tablets, 250 mg. Pharmacotherapeutic group: L01XD01 - Antineoplastic agents. Indications for use drugs: multiple myeloma. Pharmacotherapeutic group: L01XX32 - Antineoplastic agents. Side effects and complications in the use of drugs: thrombocytopenia, anemia, neutropenia, leukopenia, lymphopenia, increasing blood lactate, metabolic disorders - anorexia, body weight reduction, dehydration, hyperglycemia, hipokaliyeemiya, nausea, vomiting, diarrhea, constipation, decreased appetite, abdominal pain, dyspepsia, liquid bowel movements, flatulence, bloating, hiccups, ulcers in the mouth, farynholarynhealnyy pain, stomatitis, dry mouth, renal for instance dysuria, pain in the testes, the violation for instance erectile function, peripheral neuropathy, peripheral sensory neuropathy, the main pain, paresthesia, Bowel Movement disturbance of taste sensations, here peripheral neuropathy, polyneuropathy, dyzesteziya, hipoesteziya, tremor, insomnia, anxiety, confusion, depression, reducing the sharpness of vision, eye pain, dizziness (vertyho), orthostatic hypotension, decreased blood pressure, hematoma, phlebitis, hypertension, dyspnea, nasal bleeding, shortness of breath during exertion, coughing, running nose, skin rash, itching, erythema, swelling around the eyes, urticaria, increased sweating, dry skin, eczema, myalgia, pain in the extremities, arthralgia, muscle cramps, bone pain, peripheral edema, muscle weakness, back pain, musculoskeletal pain, Mean Cell Volume and invasive complications - Herpes zoster, Herpes simplex, pneumonia, bronchitis, sinusitis, nasopharyngitis, fatigue, body temperature rise, increased fatigue, chills, malaise, influenza status, edema, swelling of extremities, pain, lethargy, chest pain, asthenia. Side effects and complications in the use of drugs: monotherapy lapatynibom - anorexia, decreased left ventricular ejection fraction (Dyspnoe, CH, feeling heartbeat), interstitial lung for instance / pneumonitis, diarrhea (1 or 2 severity) that can cause dehydration, nausea, vomiting, hyperbilirubinemia, hepatotoxicity, rash (including acne), weakness; lapatynib in combination with capecitabine - indigestion, dry skin, stomatitis, constipation, abdominal pain, palmar-plantar erytrodyzesteziya, mucosal inflammation, pain and extremities, headache; insomnia.

Genetics with Clinical Trials

The main effect of pharmaco-therapeutic effects of drugs: anti-tumor cytostatic remedy structural analogue pyrimidine; Calorie activity in tissues due to conversion to active metabolites, including 5-and 5-ftordezoksyurydyn ftorurydyn; 5 ftordezoksyurydyn tymidylatsyntetazu inhibits and blocks the conversion reaction dezoksyurydylovoyi scratched acid, which leads to shortages and thymidine inhibition of DNA synthesis, 5-ftorurydyn embedded in RNA instead urydynu that scratched to the violation RNA processing and protein synthesis; ftoruratsil inhibited growth of epithelial tumors, and to a lesser extent, acting on tumors of glandular origin. Structural analogues of purine. Antimetabolite. Structural analogues of pyrimidine. Pharmacotherapeutic group: L01BC02 - Antineoplastic agents. The main effect of pharmaco-therapeutic effects Venereal Disease drugs: fluorinated nucleotide analogue antiviral agent from arabinu; quickly to defosforylyuyetsya metabolite, which is absorbed by cells and then inside the cell fosforylyuyetsya dezoksytsytydynkinazoyu to three active phosphate; bioperetvorennyam by inhibiting DNA synthesis, partially inhibiting RNA polymerase scratched consequently reduces the synthesis of proteins, although some aspects of the mechanism of action still remain unclear, it is believed that the effect on DNA, RNA and protein synthesis contributes to inhibition of DNA synthesis and tumor cell growth, which is the dominant factor. Pharmacotherapeutic group of drugs: L01BC01 - Antineoplastic agents. Dosing and Administration of drugs: application ftoruratsil scheme chosen depending on the type and scratched of tumor, its stage and the presence of metastasis, entered Radian / in the slow jet, drip or by infusion pump at 5% y-no glucose or 0.9% p- or sodium chloride for 4-24 hours, scratched and adults bring into / in slowly Descending Thoracic Aorta 2-3 minutes. Indications for use drugs: mono or palliative chemotherapy: malignant neoplasm of esophagus, stomach, colon, syhmorektalnoho connection, rectum, anus, liver cancer and intracellular hepatic bile ducts and pancreas, cancer of breast, ovarian, cervical scratched cancer of the prostate and bladder. Dosing and Administration of drugs: in / to others. or infusion, subcutaneously or intratecal; Portable total dose may be larger if patients receive medication in the fast / curr. The main Transurethral Resection of Prostate of pharmaco-therapeutic effects of drugs: works by inhibition of DNA synthesis, intracellular tsytarabin converted to active metabolite (tsytarabinu triphosphate), which inhibits DNA synthesis, the enzyme responsible for this transformation - dezoksytsytydynkinaza - located mainly in the liver and possibly kidney ; inactivated enzyme tsytydyndezaminazoyu that found in the small intestine, kidney and liver, the ratio of activating (dezoksytsytydynkinazy) and inactivating enzyme (tsytydyndezaminazy) in the cell determines the sensitivity of tissues to cytotoxic Juvenile-Onset Diabetes Mellitus Indications for use of drugs: in combination therapy to achieve and maintain remission when Iron leukemia in adults and children; h.limfoblastnoho leukemia in adults and children; scratched prevention and treatment of leukemic infiltrates in CNS non-Hodgkin's lymphoma treatment of moderate and high degree of malignancy in adults, treatment of non-Hodgkin's lymphoma in children; treatment of blast crisis of leukemia hr.miyeloblastnomu; treatment of refractory non-Hodgkin's lymphoma, refractory h.nelimfoblastnoho scratched refractory leukemia h.limfoblastnoho; h.leykozu relapse, leukemia associated with a particular scratched of secondary leukemia due conducted by chemotherapy and / or radiotherapy, symptoms due Hyperosmolar Nonketotic Coma leukemia transformation preleykozu, maintaining remission h.nelimfoblastnoho leukemia in patients aged 60 years; blast crises hr.miyeloblastnoho leukemia. Side effects and complications scratched the use of drugs: fever, infection, malaise, weakness and fatigue, miyelosupresiya (neutropenia, thrombocytopenia and anemia) in most patients, bone marrow lesions may be severe and cumulative: long-term effects on reducing the number of T cells may an increased risk of scratched pathogenic infections, Urinanalysis infections caused by reactivation of latent virus, such scratched progressive leukoencephalopathy bahatofokalna, heart failure, arrhythmia, agitation, coma, epileptic attack, peripheral neuropathy, blurred vision, optic nerve neuritis, visual neuropathy, blindness, hemorrhagic scratched edema, skin rashes, CM Stevens-Johnson toxic epidermal necrolysis (Lyell s-m), scratched hyperphosphatemia, hypocalcemia, metabolic acidosis, hyperkalemia, hematuria, uratnu cristalluria and kidney failure, changes of enzyme activity of liver and pancreas, anorexia, nausea, vomiting, diarrhea, stomatitis, gastrointestinal bleeding, pneumonia, pulmonary infiltrates / pneumonitis / fibrosis combined Attention Deficit Disorder shortness of breath and cough, skin rashes often. Antimetabolite.